Thiolase family
WebNov 20, 2024 · Thiolases are important enzymes involved in lipid metabolism in both prokaryotes and eukaryotes, and are essential for a range of metabolic pathways, while, little is known for this important family in insects. To shed light on the evolutionary models and functional diversities of the thiolase family, 137 thiolase genes were identified in 20 … WebJun 15, 2024 · Four red cluster proteins are assigned to the glyoxylate and dicarboxylate metabolism KEGG map, with malate dehydrogenase (EC:1.1.1.37; PMDH2) associated with the methylaspartate cycle, the thiolase family protein (EC:2.3.1.9; AACT1) associated with the ethylmalonyl pathway of terpenoid biosynthesis, and (S)-2-hydroxy-acid oxidase GLO1 …
Thiolase family
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Web我希望從網頁中檢索標題和 PMID PubMed ID 記錄並將其保存在 MS excel 文件中。 我嘗試使用 R 中的easyPubMed庫進行提取，但是，我無法獲得相同的結果。 是否有任何庫或包獲得這個。 請幫我解決這個問題。 下面提供了輸入數據和預期輸出數據的示例： 代碼： … Webthiolase. Definition from Wiktionary, the free dictionary. Jump to navigation Jump to search. English Etymology . thiol + -ase. Noun . English Wikipedia has an article on: thiolase. Wikipedia . thiolase (plural thiolases) (biochemistry) Any enzyme that catalyzes the removal of a thiol group.
WebFunction. Thiolases are a family of evolutionarily related enzymes.Two different types of thiolase are found both in eukaryotes and in prokaryotes: acetoacetyl-CoA thiolase (EC 2.3.1.9) and 3-ketoacyl-CoA thiolase (EC 2.3.1.16). 3-ketoacyl-CoA thiolase (also called thiolase I) has a broad chain-length specificity for its substrates and is involved in … WebComparative genomics analysis showed that 1,237 and 231 gene families under expansion and the yellowhorn-specific gene family NB-ARC were enriched in photosynthesis and root cap development, which may contribute to the environmental adaption and abiotic stress resistance of yellowhorn. ... A 3-ketoacyl-CoA thiolase (KAT) gene (Xso_LG02_00600 ...
WebNov 8, 2024 · Preferred Names Thiolase family protein NP_001032028.1. Thiolase family protein; FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, acetyl-CoA C-acetyltransferase activity, catalytic activity; INVOLVED IN: metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 19 plant structures; … WebOct 2, 2024 · Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several ...
WebThiolase 2 is the first enzyme in the cholesterol synthesis pathway (see Figure 6), catalyzing the conversion of two molecules of acetyl-CoA to acetoacetyl-CoA.Hydroxymethylglutaryl-CoA synthase (HMGCS) acts next, requiring water to condense acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. Cytosolic HMGCS1 synthesises mevalonic acid for cholesterol …
WebThiolases, also known as acetyl-coenzyme A acetyltransferases (ACAT), are an enzyme family that plays vital roles in lipid metabolism, including ACAT1, ACAT2, ACAA1, ACAA2, and HADHB. Our present study showed that these five members were orthologous in six livestock species including buffalo and cattle. stow n place luggage racksrotational inertia of the earthWebEnzymes of the thiolase superfamily catalyze the formation of carbon-carbon bond via the Claisen condensation reaction. Thiolases catalyze the reversible non-decarboxylative condensation of acetoacetyl-CoA from two molecules of acetyl-CoA, and possess a conserved Cys-His catalytic diad. Elongation e … stown paWebIt was suggested that thiolase family is an ancient gene family. Even in insects, the age of thiolase gene differentiation is relatively long. Thus, the discovery of fewer syntenic genes implies ... rotationally accessed spin-state inversionWebNov 20, 2024 · To shed light on the evolutionary models and functional diversities of the thiolase family, 137 thiolase genes were identified in 20 representative insect genomes. They were mainly classified into ... rotational kinetic energy of a hoopWebPeroxisomal thiolase is markedly induced (at the level of transcription) by various hypolipidemic compounds in parallel with the other two enzymes of the peroxisomal beta-oxidation system. ... Family and domain databases. CDD. cd00751 thiolase 1 hit; Gene3D. 3.40.47.10 1 hit; InterPro. View protein in InterPro; IPR002155 Thiolase; IPR016039 ... stow n place roof rackThiolases are a family of evolutionarily related enzymes. Two different types of thiolase are found both in eukaryotes and in prokaryotes: acetoacetyl-CoA thiolase (EC 2.3.1.9) and 3-ketoacyl-CoA thiolase (EC 2.3.1.16). 3-ketoacyl-CoA thiolase (also called thiolase I) has a broad chain-length specificity for its … See more Thiolases, also known as acetyl-coenzyme A acetyltransferases (ACAT), are enzymes which convert two units of acetyl-CoA to acetoacetyl CoA in the mevalonate pathway. Thiolases are … See more Mammalian nonspecific lipid-transfer protein (nsL-TP) (also known as sterol carrier protein 2) is a protein which seems to exist in two different forms: a 14 Kd protein (SCP-2) and … See more Most enzymes of the thiolase superfamily are dimers. However, monomers have not been observed. Tetramers are observed only in the thiolase subfamily and, in these cases, the dimers have dimerized to become tetramers. The crystal structure of the tetrameric … See more • Acetyl-CoA+C-Acetyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Overview of all the structural information available in the PDB See more Thioesters are more reactive than oxygen esters and are common intermediates in fatty-acid metabolism. These thioesters are made by conjugating the fatty acid with the free SH … See more In eukaryotic cells, especially in mammalian cells, thiolases exhibit diversity in intracellular localization related to their metabolic functions … See more Mitochondrial acetoacetyl-CoA thiolase deficiency, known earlier as β-ketothiolase deficiency, is an inborn error of metabolism involving isoleucine catabolism and ketone body metabolism. The major clinical manifestations of this disorder are … See more stow n place roof rack system