Web2.1 Lithium, is an option that should be considered for long-term treatment of bipolar disorder. The choice should depend on: – response to previous treatments – the relative risk, and known precipitants, of manic versus depressive relapse – physical risk factors, particularly renal disease, obesity and diabetes Web1 dec. 2016 · Lithium has been a valuable treatment for bipolar affective disorders for decades. Clinical use of lithium, however, has been problematic due to its narrow therapeutic index and concerns for its toxicity in various organ systems. Renal side effects associated with lithium include polyuria, nephrogen …
Lithium Prescribing information Bipolar disorder CKS NICE
WebKidney damage due to lithium may include acute (sudden) or chronic (long-term) kidney disease and kidney cysts. The amount of kidney damage depends on how long … Web20 jan. 2012 · Lithium is associated with increased risk of reduced urinary concentrating ability, hypothyroidism, hyperparathyroidism, and weight gain. There is little evidence for a clinically significant reduction in renal function in most patients, and the risk of end-stage renal failure is low. The risk of congenital malformations is uncertain; the balance of … sloy windyhill
Management of the renal adverse effects of lithium
Web26 mei 2024 · To minimize renal side effects, lithium is best administered once daily at night, and one should routinely use the regular-release (24-hour half-life) preparation. 1 It comes in tablets or capsules. Capsules are sometimes better tolerated because they do not have the salty taste that can contribute to nausea. Web4 jan. 2024 · Lithium-induced nephropathy is a known long-term complication, sometimes limiting the use of lithium as mood stabilizer. The aim of this study is to establish the incidence of chronic kidney disease and the rate of decline of renal function in patients using lithium and to identify risk factors. We selected 1012 patients treated with lithium … sloy scotland