Impact of mirna in atherosclerosis
WitrynaThis review highlights the impact of microRNA-33-mediated regulation in the major cardiometabolic risk factors of atherosclerosis including lipid metabolism (HDL biogenesis and cholesterol homeostasis, fatty acid, phospholipid and triglyceride, bile acids metabolism), inflammatory response, insulin signaling and glucose/energy … Witryna18 maj 2024 · To determine the influence of advanced atherosclerosis on the levels of miRNA expression in coronary plaques, we performed initially a miRNA profile using …
Impact of mirna in atherosclerosis
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WitrynaInhibition of miR-33 results in increased cholesterol efflux and HDL-cholesterol levels in mice. In this study we examined the effect of miR-33 inhibition in a mouse model of atherosclerosis and observed significant reduction in atherosclerotic plaque size. At the end of the study, gene expression in macrophages from the atherosclerotic plaques … Witryna22 lip 2024 · The authors hypothesized that ACP5, as a direct target of lncRNA-H19, causes atherosclerosis by affecting cellular proliferation and apoptosis (Huang et al. 2024). Many studies have reported that lncRNA-H19 functions as a ceRNA to sponge its target miRNAs such as microRNA let-7 (Hsu et al. 2014; Sun et al. 2024b; Cao et al. …
WitrynaAtherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its onset and progression. Nutrients have been shown to regulate the miR-17/92 cluster, … Witryna18 gru 2013 · By using a technology called "locked nucleic acids," Jo and his colleagues tested the effects of blocking miR-712 in the body. When given to mice in the rapid atherosclerosis model, the anti-miR-712 drug inhibited the development of arterial blockages. Without the drug, plaques blocked an average of 80 percent of the …
Witryna24 mar 2024 · Atherosclerosis (AS) is a chronic arterial disorder and a significant determinant of vascular death [].Fatty streaks in arterial walls regularly develop into characteristic plaques and atheroma [].The acute rupture of these atheromatous plaques leads to local thrombosis, causing partial or total occlusion of the affected artery [].AS … WitrynaScience Volunteer
Witryna19 lut 2016 · Over the past decade, microRNAs (miRNAs) have emerged as evolutionarily conserved, noncoding small RNAs that serve as important regulators …
Witryna24 cze 2024 · The inhibition of miR-33 using pHLIP-directed macrophage targeting improves atherosclerosis regression by increasing collagen content and decreased … port marcus hookWitrynaDownload scientific diagram The screened miR-342-5p facilitated the apoptosis of HUVECs impaired by H2O2. (A) The heat map of top-30 upregulated miRNAs ranked by log2FC value in RNA-sequencing ... iron age steakhouse menuWitrynaDownload scientific diagram The enriched GO terms of twenty-five overlapped genes in atherosclerosis. from publication: Adipose-derived mesenchymal stem cells-derived … port maria heart trustiron age steak house menuWitrynaAtherosclerosis is closely related to vascular dysfunction and hypertension. Ojeoksan (OJS), originally recorded in an ancient Korean medicinal book named “Donguibogam”, is a well-known, blended herbal formula. This study was carried out to investigate the beneficial effects of OJS on atherosclerosis in vitro and in vivo. Western-diet-fed … iron age soup recipeWitryna1 wrz 2024 · Request PDF On Sep 1, 2024, Yao Lu and others published Impact of miRNA in Atherosclerosis Find, read and cite all the research you need on … iron age steakhouse chicagoWitryna15 maj 2014 · The effect of miR-126-5p on atherosclerosis has been identified in vivo, which controls differentiation of smooth muscle cells, promotes lesion formation, whereas the endothelial cell-specific miR ... port marchand toulon piscine