WebJun 8, 2024 · Fanconi anaemia (FA) is a rare genetic disorder that arises due to mutations within any of the Fanconi anaemia complementation group ( FANC) genes, the products of which are involved in repair of DNA interstand crosslinks (ICLs) 2, 3 as well as in the maintenance of genomic stability in response to replication stress 4, 5. WebJul 29, 2010 · Mutations in 13 different genes implicated in repairing damaged DNA are known to be involved in the disease. Liu et al. (p. 693, published online 29 July) have identified a new factor, FAN1 (Fanconi anemia–associated nuclease 1), which they find to be associated with a complex of two of the FANC proteins, FANCI and FANCD2 (the ID …
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